Related Experiment Video
Updated: Dec 7, 2025

Real-Time Force Measurement Between Emulsion Droplets During Enzymatic Breakdown
Published on: June 27, 2025
Stability Study of Emulsion Liquid Membrane via Emulsion Size and Membrane Breakage on Acetaminophen Removal from
Nur Dina Zaulkiflee1, Abdul Latif Ahmad1, Jayasree Sugumaran1
1School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, 14300 Nibong Tebal, Malaysia.
Abstract:
The purpose of this study is to explore the emulsion liquid membrane stability for acetaminophen (ACTP) removal from aqueous solution. In this work, the membrane phase was prepared by dissolving trioctylamine (TOA) with kerosene and Span80. The stability of the emulsion in terms of emulsion size, membrane breakage, and its efficiency in removing ACTP was considered for the optimization of parameters. Investigation on the stability of emulsion was carried out by manipulating the concentration of stripping agent, agitation speed, extraction time, and treat ratio. The best condition to produce a very stable emulsion was achieved at 0.1 M of stripping agent concentration, with 300 rpm of agitation speed for 3 min of extraction time with a treat ratio of 3:1. Eighty-five percent of ACTP successfully stripped into the emulsion with minimum membrane breakage of 0.17% through this experiment.
Related Concept Videos
Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH
A drug's pKa and the pH of the gastrointestinal (GI) tract play crucial roles...
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
Membrane Fluidity
Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

