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Left Ventricular Thrombus With COVID-19 Complication in a Patient With Dilated Cardiomyopathy
Shohei Imaeda1, Hiroki Kabata2, Yasuyuki Shiraishi1
1Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Insights
Coronavirus disease 2019 (COVID-19) can cause arterial thrombosis, a rare complication. This case highlights a left ventricular thrombus in a COVID-19 patient with dilated cardiomyopathy, successfully treated with anticoagulation.
Area of Science:
- Cardiology
- Infectious Diseases
- Thrombosis Research
Background:
- Venous thromboembolism is a known complication of COVID-19.
- Arterial thrombosis is less commonly reported in coronavirus disease 2019 patients.
Observation:
- A patient with non-severe COVID-19 and dilated cardiomyopathy presented with improving clinical symptoms.
- Despite clinical improvement, D-dimer levels progressively increased.
- Diagnostic imaging revealed a left ventricular thrombus.
Findings:
- The left ventricular thrombus in this COVID-19 case was successfully treated with anticoagulant therapy.
- The patient experienced thrombus resolution and clinical recovery.
- This case underscores the potential for rare arterial thrombotic events in COVID-19.
Implications:
- Early diagnosis and appropriate management of left ventricular thrombus are crucial in COVID-19 patients, especially those with underlying cardiac conditions like dilated cardiomyopathy.
- This case emphasizes the need for vigilant monitoring of thrombotic markers and diagnostic imaging in specific COVID-19 patient populations.
- Further research into the mechanisms of arterial thrombosis in COVID-19 is warranted to improve patient outcomes.
Abstract:
Thrombosis, especially venous thromboembolism, is a complication often associated with coronavirus disease 2019 (COVID-19). However, there have been relatively few reports of arterial thrombosis. Here, we describe a case of non-severe COVID-19 in a patient with dilated cardiomyopathy. After admission, symptoms, laboratory data, and imaging findings improved, but D-dimer levels gradually increased. Contrast computed tomography and echocardiography revealed a left ventricular thrombus. Anticoagulant treatment diminished the thrombus, and the patient recovered and was discharged. Although a left ventricular thrombus is a rare COVID-19 complication, performing appropriate diagnostic tests could improve COVID-19 mortality in patients with dilated cardiomyopathy.
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