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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

129
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
94
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
158
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

111
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
111
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

110
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
110
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
130

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Updated: Dec 7, 2025

Oral Health Assessment by Lay Personnel for Older Adults
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Nutritional status among elderly: A community-based cross-sectional study.

Kriti Vaish1, Somdatta Patra2, Pragti Chhabra3

  • 1Senior Resident, Department of Community Health, St. Stephen's Hospital, New Delhi, India.

Indian Journal of Public Health
|September 28, 2020
PubMed
Summary

Nearly half of elderly individuals in Delhi exhibit possible malnutrition. Key risk factors include advanced age, being a tenant, and financial dependency, highlighting the need for early detection and intervention strategies for healthy aging.

Keywords:
CommunityMini Nutritional Assessmentelderlynutrition

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Area of Science:

  • Gerontology
  • Public Health
  • Nutritional Science

Background:

  • Malnutrition among the elderly is a critical public health issue with severe health consequences.
  • Community-based studies on elderly malnutrition, particularly in India, are scarce.

Purpose of the Study:

  • To determine the prevalence of malnutrition in elderly individuals residing in urbanized villages of Delhi.
  • To identify risk factors associated with malnutrition in this population.

Main Methods:

  • A cross-sectional study involving 353 individuals aged over 60 years was conducted in East Delhi.
  • Data collected via semi-structured interviews and the Mini Nutritional Assessment (MNA) scale.
  • Statistical analyses included descriptive statistics, Chi-square tests, and multivariable logistic regression.

Main Results:

  • The prevalence of possible malnutrition was 49.3%.
  • Bivariate analysis revealed associations between malnutrition and age, gender, education, marital status, income, financial dependency, and family size (P < 0.05).
  • Significant predictors for possible malnutrition included age >70 years, tenant status, and financial dependency.

Conclusions:

  • Early identification of malnutrition using appropriate tools is crucial for effective interventions and promoting healthy aging.
  • Socioeconomic factors are closely linked to elderly malnutrition and should be integrated into prevention strategies.