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Transcatheter "valve-in-valve" mitral valve replacement for patient-prosthesis mismatch: Chronicle of a death
Mateo Marin-Cuartas1, Thilo Noack1, Philipp Kiefer1
1University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany.
Abstract:
Severe mitral annular calcification (MAC) may represent a challenging issue which can lead to poor outcomes and serious issues such as patient-prosthesis mismatch (PPM). The potential harmful effect of PPM must be prevented through the use of alternative techniques that allow mitral valve replacement with adequately sized bioprostheses in patients with MAC. PPM should be recognized as a contraindication for transcatheter valve-in-valve replacement as it leads to poor outcomes and early prosthetic degeneration.
Insights
Severe mitral annular calcification (MAC) poses risks like patient-prosthesis mismatch (PPM). Alternative techniques are crucial for mitral valve replacement in MAC patients to prevent PPM and ensure better outcomes.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Biomedical Engineering
Background:
- Severe mitral annular calcification (MAC) presents significant challenges in mitral valve replacement.
- Patient-prosthesis mismatch (PPM) is a potential complication associated with MAC, leading to adverse outcomes.
Observation:
- MAC can complicate the selection of appropriately sized bioprostheses during mitral valve replacement.
- Transcatheter valve-in-valve replacement may be unsuitable in MAC patients due to the high risk of PPM.
Findings:
- Alternative surgical techniques are necessary to ensure adequate bioprosthesis sizing in MAC patients.
- PPM must be avoided to prevent poor clinical outcomes and premature prosthetic degeneration.
Implications:
- Developing and utilizing alternative mitral valve replacement strategies is critical for patients with severe MAC.
- Recognizing PPM as a contraindication for transcatheter valve-in-valve replacement in MAC is essential for patient safety and prosthesis longevity.
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