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Updated: Dec 7, 2025

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
Published on: September 17, 2017
Perspectives of DCDR-GERS in the analysis of amino acids
Václav Ranc1, Zuzana Chaloupková
1Regional Centre of Advanced Technologies and Materials, Palacky University Olomouc, 17. Listopadu 12, 771 46 Olomouc, Czech Republic. vaclav.ranc@upol.cz.
Abstract:
Graphene-enhanced Raman scattering (GERS) has attracted increasing attention from many scientists in recent years as a novel and potentially strong analytical technique since its discovery in 2010. GERS combines the ultra-high sensitivity and spectral analysis of the structural properties of many molecules found in surface-enhanced Raman scattering (SERS) and graphene simple sample processing and excellent uniformity. This facilitates a fast and very sensitive analysis of a wide range of analytes. Here, we present a new method for amino acid analysis based on the combination of drop coating deposition Raman (DCDR) and GERS. The potential of the method was evaluated in the analyses of Trp, Leu, Phe, and DOPA. Achievable limits of detection for all the studied amino acids are in tens of ng mL-1.
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