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C4 nephritic factor in a patient with chronic glomerulonephritis
Journal of Clinical & Laboratory Immunology
|February 1, 1987
Summary
A novel C4 nephritic factor (C4NeF) was identified in a patient with chronic glomerulonephritis, stabilizing the C4b2a enzyme and potentially causing low C3 levels. The factor
Area of Science:
- Immunology
- Nephrology
- Complement System
Background:
- Chronic glomerulonephritis is associated with complement system dysregulation.
- Low C3 levels (<1% of normal) were observed in a patient with chronic glomerulonephritis.