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Gut microbes in cardiovascular diseases and their potential therapeutic applications

Ling Jin1, Xiaoming Shi2, Jing Yang2

  • 1Center of Basic Medical Research, Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, 100191, China.

Protein & Cell
|September 29, 2020
PubMed

Insights

The gut microbiome influences human health, with imbalances linked to chronic diseases like cardiovascular diseases (CVDs). This review explores the gut microbiome

Area of Science:

  • Microbiology
  • Human Health
  • Cardiovascular Science

Background:

  • The intestinal microbiome is a complex bacterial community crucial for human health.
  • Microbial community imbalances are associated with various chronic diseases.
  • Cardiovascular diseases (CVDs) are a major global health concern influenced by multiple factors.

Purpose of the Study:

  • To review the intricate relationship between the gut microbiome and cardiovascular diseases (CVDs).
  • To explore the role of microbial metabolites in CVD development.
  • To discuss the therapeutic potential of modulating the gut microbiome for CVD treatment.

Main Methods:

  • Literature review of recent scientific evidence.
  • Analysis of the interplay between gut microbes, metabolites, and CVD.
  • Discussion of potential future therapeutic strategies.

Main Results:

  • Growing evidence links gut microbiome composition and function to CVD.
  • Microbial metabolites can influence the pathogenesis of cardiovascular diseases.
  • The gut microbiome represents a potential target for novel CVD therapies.

Conclusions:

  • The gut microbiome plays a significant role in the development of cardiovascular diseases.
  • Modulating the gut microbiome offers promising therapeutic avenues for CVD.
  • Future clinical applications of gut microbial interventions for CVD are anticipated.

Keywords:
action mechanismcardiovascular diseasesgut microbiotatherapeutic applications

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