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Development of the Heart01:27

Development of the Heart

1.7K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
1.7K
Chambers of the Heart01:16

Chambers of the Heart

9.3K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
9.3K
Anatomy of the Heart01:27

Anatomy of the Heart

117.3K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
117.3K
Anatomy of the Heart01:20

Anatomy of the Heart

1.8K
The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
1.8K
Development of Blood Vessels01:07

Development of Blood Vessels

1.2K
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
1.2K
Physiology of the Heart: The Cardiac Cycle01:18

Physiology of the Heart: The Cardiac Cycle

6.4K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
6.4K

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Related Experiment Video

Updated: Dec 7, 2025

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution
07:30

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution

Published on: October 7, 2016

8.5K

A New Link to Primate Heart Development.

Raman V Nelakanti1, Andrew Z Xiao1

  • 1Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA.

Developmental Cell
|September 29, 2020
PubMed
Summary
This summary is machine-generated.

A primate long non-coding RNA (lncRNA), BANCR, is crucial for fetal heart development. This study shows BANCR promotes cell migration in developing cardiomyocytes.

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Related Experiment Videos

Last Updated: Dec 7, 2025

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution
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Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution

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En Face Endocardial Cushion Preparation for Planar Morphogenesis Analysis in Mouse Embryos
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En Face Endocardial Cushion Preparation for Planar Morphogenesis Analysis in Mouse Embryos

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Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells
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Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells

Published on: September 15, 2021

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Area of Science:

  • Developmental Biology
  • RNA Biology
  • Stem Cell Research

Background:

  • Long non-coding RNAs (lncRNAs) are key regulators in biological development.
  • Understanding the specific roles of lncRNAs in organogenesis is crucial.

Purpose of the Study:

  • To investigate the function of the primate lncRNA BANCR in development.
  • To determine the expression pattern and cellular effects of BANCR in fetal cardiomyocytes.

Main Methods:

  • Utilized pluripotent stem cell models.
  • Analyzed BANCR expression in fetal cardiomyocytes.
  • Assessed the impact of BANCR on cardiomyocyte migration.

Main Results:

  • BANCR is predominantly expressed in fetal cardiomyocytes.
  • BANCR was found to significantly promote cell migration in these cells.

Conclusions:

  • The primate lncRNA BANCR plays a vital role in fetal cardiomyocyte development.
  • BANCR's function in promoting cell migration is essential for cardiac development.