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Updated: Dec 7, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
A Case of Anaphylaxis in Which a Basophil Activation Test Was Used to Identify the Suspected Agent
Takashi Goto1, Shintaro Hayashi1, Hiroko Tsugane2
1Department of Dental Anesthesiology, Division of Oral Pathogenesis and Disease Control, Asahi University School of Dentistry, Gifu, Japan.
Abstract:
This is a case report of anaphylaxis in which the basophil activation test (BAT) was used to identify the etiological agent. Although skin tests are considered the most effective methods for identifying anaphylactic triggers, the test itself presents a risk of inducing anaphylaxis. The BAT is advantageous because of its inherent lack of risk, high sensitivity and specificity to identify the suspected anaphylactic agents, and diagnostic accuracy comparable to conventional skin testing. Therefore, in the future, the BAT is likely to become the preferred test for the detection of allergens over conventional skin tests.
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