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Primary Retrobulbar Leiomyosarcoma in a Dog: A Case Report
Joong-Hyun Song1, Do-Hyeon Yu1, Dong-In Jung1
1Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.
A rare retrobulbar leiomyosarcoma, a type of undifferentiated sarcoma, was diagnosed in a dog. This case highlights the clinical, imaging, and histopathological features of this aggressive tumor.
Area of Science:
- Veterinary Pathology
- Canine Oncology
Background:
- Retrobulbar tumors in dogs can present with varied clinical signs.
- Leiomyosarcoma is a rare malignant mesenchymal tumor originating from smooth muscle.
Observation:
- A 2-year-old dog exhibited progressive exophthalmos and periorbital swelling.
- Imaging revealed a retrobulbar mass invading the nasal cavity and brain.
- Cytology indicated a malignant mesenchymal tumor.
Findings:
- Histopathology and immunohistochemistry confirmed undifferentiated sarcoma, consistent with leiomyosarcoma.
- Tumor cells were positive for vimentin, smooth muscle actin, and desmin.
- The tumor infiltrated surrounding bone and brain tissue.
Implications:
- This case expands the understanding of primary retrobulbar leiomyosarcoma in dogs.
- Early diagnosis and advanced imaging are crucial for managing such rare canine tumors.
- Further research is needed to explore treatment options for retrobulbar leiomyosarcoma.
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