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Related Experiment Videos

Indications for immunotherapy.

A M Solinger

    Pharmacotherapy
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Immunodeficiency, characterized by recurrent infections, can be primary or secondary. Various immunotherapies, including immunoglobulin therapy and tissue transplantation, offer treatment options for these immune system disorders.

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    Area of Science:

    • Immunology
    • Medical Science

    Background:

    • Immunodeficiency should be considered in patients with recurrent, severe, or unusual infections.
    • Immune defects can be primary or secondary, affecting specific or nonspecific immune mechanisms.

    Purpose of the Study:

    • To review the classification and immunotherapeutic modalities for primary and secondary immunodeficiency disorders.

    Main Methods:

    • Literature review of existing immunotherapeutic strategies.
    • Classification of immunodeficiency based on immune mechanisms.

    Main Results:

    • Intravenous immunoglobulin therapy is a significant treatment option.
    • Tissue transplantation (bone marrow, fetal liver, fetal thymus) is another therapeutic approach.

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  • Emerging therapies include enzyme replacement, thymus extracts, interleukins, and transfer factors.

    • Conclusions:

    • A range of immunotherapies are available for primary and secondary immunodeficiencies.
    • Nonspecific immune modulators may be useful in tumor immunotherapy.