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Updated: Dec 7, 2025

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
Published on: May 15, 2014
Construction of Stable Reporter Flaviviruses and Their Applications
Coleman Baker1, Pei-Yong Shi2,3,4,5,6
1Microbiology and Immunology Department, University of Texas Medical Branch, Galveston, TX 77555, USA.
Abstract:
Flaviviruses are significant human pathogens that cause frequent emerging and reemerging epidemics around the world. Better molecular tools for studying, diagnosing, and treating these diseases are needed. Reporter viruses represent potent tools to fill this gap but have been hindered by genetic instability. Recent advances have overcome these hurdles, opening the way for increased use of stable reporter flaviviruses to diagnose infections, screen and study antiviral compounds, and serve as potential vaccine vectors.

