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Updated: Dec 7, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
[Nutrition and microbiota in pediatric population. Health implications].
Ana Isabel Jiménez Ortega1, Rosa María Martínez García2, Marta Velasco Rodríguez-Belvis3
1Unidad de Gastroenterología Pediátrica. Hospital San Rafael.
This review explores the scientific evidence for probiotic efficacy in various health conditions. It aims to clarify which probiotic applications are supported by research and clinical guidelines for restoring gut microbiota balance.
Area of Science:
- Microbiology
- Gastroenterology
- Immunology
Background:
- The human body hosts a complex microbiota crucial for health.
- Microbiota dysbiosis is linked to various diseases.
- Probiotics are explored as a method to modulate microbiota and restore balance.
Purpose of the Study:
- To review and summarize evidence-based indications for probiotic use.
- To identify probiotic applications supported by scientific guides and studies.
- To provide clarity on the effectiveness of different probiotics for specific conditions.
Main Methods:
- Literature review of scientific studies.
- Analysis of clinical guidelines on probiotic use.
- Synthesis of evidence for various probiotic applications.
Main Results:
- Evidence varies significantly across different probiotic strains and indications.
- Specific probiotic uses are supported by robust scientific data.
- Not all marketed probiotics are effective for all claimed health benefits.
Conclusions:
- Probiotic efficacy is strain-specific and indication-dependent.
- Informed selection of probiotics based on evidence is crucial for therapeutic success.
- Further research is needed to fully elucidate probiotic mechanisms and applications.
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