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Cardiovascular clinical trials in the era of a pandemic

George Cm Siontis1, Romy Sweda1, Stephan Windecker1

  • 1Department of Cardiology Bern University Hospital Bern Switzerland.

Journal of the American Heart Association
|September 30, 2020
PubMed

Insights

The COVID-19 pandemic disrupted clinical research unrelated to the virus, posing challenges for researchers and participants. Maintaining trial integrity requires overcoming logistical hurdles and data collection issues.

Area of Science:

  • Public Health
  • Clinical Research Management

Background:

  • The COVID-19 pandemic, declared in March 2020, significantly impacted global public health.
  • Clinical research unrelated to COVID-19 faced substantial disruptions.

Discussion:

  • Researchers, participants, and staff encountered numerous challenges.
  • These include logistical difficulties, reduced patient enrollment, and issues with follow-up and data collection.

Key Insights:

  • The pandemic's consequences on clinical trials are unpredictable and far-reaching.
  • Sustaining the proper and safe conduct of clinical trials is a major concern.

Outlook:

  • Future clinical research may face prolonged funding issues.
  • Adaptation strategies are crucial for navigating pandemic-related research challenges.

Keywords:
COVID‐19cardiovascular diseasecardiovascular researchrandomized controlled trial

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