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Updated: Dec 7, 2025

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage
Published on: April 28, 2022
Impact of preoperative chlorhexidine gluconate (CHG) application methods on preoperative CHG skin concentration
Bobby G Warren1,2, Alicia Nelson1,2, David K Warren3
1Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, North Carolina.
Abstract:
Elective surgical patients routinely bathe with chlorhexidine gluconate (CHG) at home days prior to their procedures. However, the impact of home CHG bathing on surgical site CHG concentration is unclear. We examined 3 different methods of applying CHG and hypothesized that different application methods would impact resulting CHG skin concentration.
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