Related Experiment Video
Updated: Dec 7, 2025
Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells
Published on: February 21, 2019
GUMBOS and nanoGUMBOS in chemical and biological analysis: A review
Ana M O Azevedo1, João L M Santos1, Isiah M Warner2
1LAQV, REQUIMTE, Departamento de Ciências Químicas, Laboratório de Química Aplicada, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
Abstract:
GUMBOS (group of uniform materials based on organic salts) is a novel class of materials that exhibits similar features to those of ionic liquids, but have melting points between 25 and 250 °C. GUMBOS can be easily converted into nanomaterials (nanoGUMBOS), with advantages of working at nanoscale. Due to the huge number of possible cation-anion combinations, these materials can be multifunctional and designed for a specific task. This review highlights the possibility of fine-tuning GUMBOS physical and chemical properties in view of changing their ionic counterparts. Their outstanding potential for analytical applications is shown through recent developments in areas such as sensing, and solid-phase extraction. Available methods for synthesis of nanoGUMBOS, and their different outcomes in shapes and optical properties are described, with pros and cons being outlined. Finally, an analysis is made of opportunities and challenges faced by this class of organic ionic materials.
