Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent advances in the management of small bowel Crohn's disease.

The Korean journal of internal medicine·2026
Same author

Probing Site-Specific Magnetism in Time-Reversal-Odd Antiferromagnet via Electric Field-Induced Nonreciprocal Directional Dichroism.

Physical review letters·2026
Same author

Suspected autoimmune cerebellar ataxia: Predictors of immunotherapy response and diagnosis reclassification to neurodegenerative disease.

Journal of the neurological sciences·2026
Same author

Raman Optical Activity Induced by Ferroaxial Order in NiTiO_{3}.

Physical review letters·2026
Same author

Early neural shift detection using functional magnetic resonance imaging: a pilot study with Parkinson's disease patients undergoing istradefylline and hybrid assistive limb interventions.

Frontiers in neurology·2026
Same author

Association between individual cerebral small vessel disease MRI markers and neuropsychological performance in amnestic mild cognitive impairment: an exploratory study.

Journal of neurology·2026

Related Experiment Video

Updated: Dec 7, 2025

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
12:54

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Published on: February 12, 2013

12.8K

Preparation of gradient-type biological tissue-polymer complex for interlinking device.

Yongwei Zhang1, Kwangwoo Nam1, Tsuyoshi Kimura1

  • 1Department of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

Materials Science & Engineering. C, Materials for Biological Applications
|September 30, 2020
PubMed
Summary

Decellularized dermis absorbs monomers based on tissue structure, not surface energy. Sonication enhances absorption, enabling gradient polymer complex preparation with improved mechanical strength.

Keywords:
AbsorptionDecellularised dermisGradient-type complexInterlinking deviceSonication

More Related Videos

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.0K
Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
12:19

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Published on: July 1, 2013

11.1K

Related Experiment Videos

Last Updated: Dec 7, 2025

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
12:54

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Published on: February 12, 2013

12.8K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.0K
Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
12:19

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Published on: July 1, 2013

11.1K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Polymer Chemistry

Background:

  • Decellularized dermis is a promising biomaterial for tissue regeneration.
  • Controlling the interaction between decellularized tissues and polymers is crucial for developing advanced biomaterials.
  • Understanding monomer absorption is key to creating functional tissue-polymer composites.

Purpose of the Study:

  • To investigate monomer absorption in decellularized dermis.
  • To prepare a gradient-type decellularized dermis-polymer complex.
  • To evaluate the mechanical properties of the resulting complex.

Main Methods:

  • Decellularization of dermis using sodium dodecyl sulfate.
  • Investigation of monomer absorption using hydrophobic monomers with varying surface free energies.
  • Enhancement of monomer absorption via sonication.
  • Preparation of a gradient decellularized dermis-poly(methyl methacrylate) complex by controlling monomer permeation time.

Main Results:

  • Monomer absorption is primarily dependent on tissue structure, irrespective of surface free energy.
  • Sonication significantly increases the amount of absorbed monomer.
  • A gradient complex with gradually increasing mechanical strength from dermis to polymer was successfully prepared.
  • The complex integrates the physical properties of both decellularized dermis and poly(methyl methacrylate).

Conclusions:

  • Decellularized dermis exhibits structure-dependent monomer absorption.
  • Sonication is an effective method to enhance monomer uptake in decellularized tissues.
  • Gradient decellularized dermis-polymer complexes can be fabricated with tailored mechanical properties.
  • These gradient composites offer a combination of biological and mechanical advantages for potential applications.