Related Experiment Video
Updated: Dec 7, 2025
Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
Comparative molecular docking analysis of the SARS CoV-2 Spike glycoprotein with the human ACE-2 receptors and
Piyush Bhanu1,2, Nisha Hemandhar Kumar1, Shamini Hemandhar Kumar3
1Xome Life Sciences, Bangalore Bioinnovation Centre, Helix Biotech Park, Bengaluru, Karnataka-560100,India.
Abstract:
Comparative molecular docking and vixualization analysis of the human thrombin with the SARS CoV-2 Spike glycoprotein and the human ACE-2 receptors is of interest. The data shows that residues spanning positions 30-41 in the ACE-2 have interaction with the spike glycoprotein (UniProt ID: Q9BYF1). Results also shows that thrombin binds with SER494 in the spike protein, and GLU37 in the ACE2 receptor. SER494 in the viral receptor-binding domain provides support for hotspot-353 reported elsewhere. These preliminary data provide insights for further probe.
More Related Videos
06:39High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells
Published on: April 21, 2022
08:07Author Spotlight: Advancing Antiviral Strategies Through Novel Immunocapture and Mass Spectrometry Techniques
Published on: January 12, 2024
