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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Tracheal leiomyoma mimicking asthma for over 20 years
Oliver J Harrison1, Mark Jackson2, Emily Shaw3
1Department of Thoracic Surgery, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Abstract:
Benign tracheal tumours have an incidence of 1 in 1,000,000, of which leiomyomas represent only 1%. We report a case of tracheal leiomyoma masquerading as asthma for over 20 years. A 48-year-old man presented aged 26 years with asthma symptoms unresponsive to treatments and an obstructive spirometry pattern. Symptoms were not particularly troubling but suddenly exacerbated 22 years later. Flow-volume studies were consistent with upper airway obstruction. Computed tomography chest revealed a 2.3 cm mass arising from the posterior aspect of the trachea 2 cm above the carina. Bronchoscopic resection was performed using a Nd:YAG laser. Histology confirmed leiomyoma. Follow-up after 6 weeks revealed complete resolution of symptoms with normal spirometry. Tracheal masses should be considered in any patient with atypical asthma. A flow-volume loop may provide a clue to diagnosis and bronchoscopic laser resection is a minimally invasive treatment option.
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