Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
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Published on: September 9, 2015
V Thadchanamoorthy1, Kavinda Dayasiri2
1Honorary Consultant Paediatrician & Senior Lecturer, Clinical Science Department, Faculty of Health Care Sciences, Eastern University, Sri Lanka.
Insights
Infant tuberculosis can present unusually, even with lung abscesses and no typical symptoms. Early suspicion and diagnosis are vital for better outcomes in young children with this serious infection.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pulmonology
Background:
- Tuberculosis (TB) in infants carries a high risk of severe disease and mortality.
- Lung abscesses are rare in infants with TB, typically following bacterial infections.
Observation:
- A 10-month-old infant presented with extensive pulmonary TB, lung abscess, and pleural effusions.
- The infant showed atypical symptoms: no cough, poor growth, or fever, with minimal inflammatory markers.
Findings:
- Pulmonary tuberculosis diagnosis was confirmed via polymerase chain reaction (PCR).
- The infant achieved full clinical and radiological recovery after a six-month anti-TB drug regimen.
Implications:
- Clinicians must maintain a high suspicion for TB in infants, regardless of age or symptoms.
- Delayed diagnosis in infants significantly worsens tuberculosis outcomes, underscoring the need for prompt recognition.
Abstract:
Tuberculosis in infants although less common compared to older children and adults, is associated with a high risk for milliary tuberculosis, tuberculosis meningitis and overall higher mortality. Lung abscess commonly presents following severe community acquired bacterial infections and is extremely rare in infants with tuberculosis. This report presents the case of a 10-month-old infant who had an unusual presentation of pulmonary tuberculosis with no cough, poor growth or documented temperature >38 C despite extensive right lung involvement with lung abscess formation and pleural effusions. Inflammatory markers were minimally deranged. The diagnosis of pulmonary tuberculosis was confirmed based on positive tuberculosis polymerase chain reaction test. The child made a successful clinical and radiological recovery upon completion of anti-tuberculosis drug regimen for six months. This report brings to light that it is crucial for clinicians to have a high index of suspicion of tuberculosis irrespective of age of the patient, presenting symptoms and low prevalence since delayed diagnosis of tuberculosis in infants is associated with poor outcomes.
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