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Related Experiment Video

Updated: Dec 7, 2025

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Endoscopic transoral nasopharyngectomy.

Roberto M Soriano1, Rima S Rindler2, Samuel N Helman3

  • 1Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.

Head & Neck
|September 30, 2020
PubMed
Summary

Endoscopic transoral nasopharyngectomy (ETON) is a feasible minimal access technique for resecting large nasopharyngeal tumors. This natural orifice approach offers wide skull base exposure and proximal control of the internal carotid artery.

Keywords:
endoscopicendoscopic transoral surgerynasopharyngectomynasopharynxskull base surgery

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Area of Science:

  • Otolaryngology
  • Head and Neck Surgery
  • Minimally Invasive Surgery

Background:

  • Management of nasopharyngeal tumors with inferolateral extension presents challenges for traditional surgical approaches.
  • A need exists for minimal access techniques for complex nasopharyngeal tumor resections.

Purpose of the Study:

  • To demonstrate the feasibility of endoscopic transoral nasopharyngectomy (ETON) for large nasopharyngeal lesions.
  • To evaluate ETON as a natural orifice alternative to conventional surgical methods.

Main Methods:

  • The study involved three latex-injected cadaveric specimens.
  • Surgical freedom (SF) and angles of attack (AoA) were calculated relative to the internal carotid artery (ICA).

Main Results:

  • Endoscopic transoral nasopharyngectomy was successfully performed, enabling identification and control of the parapharyngeal ICA.
  • Maximal SF and sagittal AoA were observed at the anterior genu of the ICA.

Conclusions:

  • Endoscopic transoral nasopharyngectomy (ETON) is a feasible surgical technique.
  • ETON provides extensive skull base visualization and proximal control of the ICA.
  • This approach may be suitable for nasopharyngeal tumors with inferolateral extension involving the ICA.