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Estimating worldwide current antibiotic usage: report of Task Force 1.

N F Col, R W O'Connor

    Reviews of Infectious Diseases
    |May 1, 1987
    PubMed
    Summary

    Antibiotic availability data from global sources reveal significant variations in human antibiotic consumption worldwide. These estimates highlight differing usage patterns across countries and over time.

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    Area of Science:

    • Pharmacology
    • Global Health
    • Drug Utilization Studies

    Background:

    • Antibiotic availability serves as a proxy for human antibiotic consumption patterns.
    • Understanding global antibiotic use is crucial for antimicrobial stewardship and resistance monitoring.

    Purpose of the Study:

    • To estimate global antibiotic availability as an indicator of human antibiotic use.
    • To analyze availability data by major antibiotic classes and individual products.

    Main Methods:

    • Collected antibiotic availability data from various countries worldwide.
    • Organized data by antibiotic class (penicillins, cephalosporins, tetracyclines, erythromycins) and individual products.
    • Converted data to units of weight and defined daily dosages per 1,000 population per day, using sales or production/trade data.

    Main Results:

    • Significant variations in antibiotic availability were observed among different countries.
    • Year-to-year fluctuations in antibiotic availability were noted within the same country.
    • Global production data for key antibiotic classes were incorporated into the estimates.

    Conclusions:

    • Antibiotic availability estimates provide valuable insights into global human antibiotic consumption.
    • Wide variations underscore the need for context-specific antimicrobial stewardship strategies.
    • Further research into factors influencing these availability patterns is warranted.

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