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Cognitive performance in midlife type 2 diabetes: results from the ENBIND study
Diabetic Medicine : a Journal of the British Diabetic Association
|September 30, 2020
Summary
Type 2 diabetes in midlife adults is linked to significant cognitive declines, particularly in memory and learning. Early identification of these changes may aid in preventing future cognitive impairment.
Area of Science:
- Neuroscience
- Endocrinology
- Gerontology
Background:
- Type 2 diabetes is a growing global health concern.
- Cognitive impairment is a known complication of diabetes, but its impact in midlife is less understood.
Purpose of the Study:
- To investigate the effects of uncomplicated type 2 diabetes on cognitive and neuropsychological functioning in middle-aged adults.
Main Methods:
- A cross-sectional study compared middle-aged adults with type 2 diabetes to healthy controls.
- Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and a detailed neuropsychological battery.
Main Results:
- Participants with type 2 diabetes were over twice as likely to err on the MoCA.
- Type 2 diabetes was associated with significantly lower memory composite and paired associates learning scores, even after adjusting for confounding factors.
Conclusions:
- Midlife type 2 diabetes is associated with subtle yet significant cognitive decrements.
- These findings highlight the potential for early detection of cognitive risks in midlife individuals with type 2 diabetes for preventative strategies.
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