Incidence, Characteristics, and Outcomes of Emergent Isolated Coronary Artery Bypass Grafting

Mohamed Farouk Elsisy1, John M Stulak2, Mohamad Alkhouli2

  • 1Department of Cardiovascular Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.

Insights

The incidence of emergency coronary artery bypass surgery (CABG) significantly decreased from 1993 to 2019, particularly for cases arising from percutaneous coronary intervention complications. Despite advancements, in-hospital mortality for emergent CABG remained stable.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Health Outcomes Research

Background:

  • Emergency coronary artery bypass surgery (CABG) data are scarce, necessitating analysis of trends and outcomes.
  • Understanding the evolution of emergent CABG indications and patient profiles is crucial for surgical practice.
  • The study examines a large cohort over an extended period to identify changes in emergent CABG procedures.

Purpose of the Study:

  • To analyze trends in the incidence and indications of emergent isolated CABG.
  • To evaluate in-hospital outcomes and long-term survival associated with emergent CABG.
  • To compare patient characteristics and procedural outcomes across different time eras.

Main Methods:

  • Retrospective analysis of 14,455 isolated CABG patients at Mayo Clinic (1993-2019).
  • Categorization of emergent CABG cases into three eras: 1993-2000, 2001-2010, and 2011-2019.
  • Kaplan-Meier survival analysis stratified by indication; comparison of baseline characteristics and in-hospital outcomes.

Main Results:

  • The incidence of emergent CABG decreased from 2.95% overall to 55 cases in the latest era (2011-2019).
  • A decline in emergent CABG due to failed percutaneous coronary intervention was observed (38.2% to 22.7%).
  • Internal mammary graft use increased to 100% in the recent era; operative mortality was 8.7% overall, with no significant temporal increase, though renal failure incidence rose.

Conclusions:

  • A significant temporal decrease in emergent CABG incidence was observed, linked to improved percutaneous coronary intervention outcomes.
  • Despite increased heart failure prevalence and complete revascularization, in-hospital mortality for emergent CABG did not rise.
  • Long-term survival was consistent across different emergent CABG indications.

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