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Updated: Dec 7, 2025

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
Published on: May 10, 2024
Postoperative negative pressure wound therapy is associated with decreased surgical site infections in all lower
Owen B Gantz1, Nicole D Rynecki2, Ashok Para1
1Department of Orthopaedic Surgery, Rutgers New Jersey Medical School, Rutgers University, Newark, NJ, USA.
Introduction:
We hypothesize that Negative Pressure Wound Therapy (NPWT) is associated with a lower incidence of surgical site infection (SSI) in lower extremity amputations (LEAs), a potentially devastating complication.
Methods:
NSQIP database from 2011 to 2018 was queried to identify all-level LEAs. Cases using NPWT were identified. One-to-one nearest-neighbor propensity score matching was performed using a binary logistic regression on NPWT status controlling for patient comorbidities.
Results:
NPWT was used in 133 of 5237 total LEAs (2.54%). Compared to propensity score-matched controls, they had significantly fewer SSIs (1.50% vs. 8.27%).
Conclusions:
NPWT was associated with lower incidence of SSI.
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