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Summary
This summary is machine-generated.

Dietary reference intakes (DRIs) are standards for healthy people. However, chronic diseases alter nutrient needs, requiring special consideration for individuals with specific health conditions.

Keywords:
Dietary Reference Intakeschronic diseaseinborn errors of metabolismpreventionspecial nutrient requirements

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Area of Science:

  • Nutrition Science
  • Clinical Nutrition
  • Public Health

Background:

  • Dietary reference intakes (DRIs) are established for healthy populations.
  • Chronic diseases are a growing global health concern, particularly in older adults.
  • Nutrient requirements can change significantly in various disease states and clinical conditions.

Purpose of the Study:

  • To review the scientific literature on disease-altering nutrient requirements.
  • To highlight the need for specialized nutritional guidance in clinical settings.
  • To support the integration of disease-specific needs into nutrition policy.

Main Methods:

  • Literature review of studies examining nutrient requirements in disease states.
  • Analysis of examples demonstrating altered nutrient needs due to illness or treatment.
  • Synthesis of evidence on conditionally essential nutrients and toxicity at altered levels.

Main Results:

  • Disease and its treatment can lead to nutrient depletion or excess.
  • Biochemical changes in disease may necessitate nonessential nutrients or cause toxicity.
  • Examples from literature illustrate significant shifts in nutrient requirements.

Conclusions:

  • Standard DRIs may not be adequate for individuals with chronic diseases.
  • Altered nutrient requirements in disease necessitate tailored dietary recommendations.
  • Further research and consideration of disease-specific needs are crucial for effective nutrition guidance.