[Corrigendum] MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro

Chen-Xing Ji1, Yang-Hua Fan1, Fan Xu2

  • 1Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330000, P.R. China.

Oncology Reports
|October 1, 2020
PubMed

Insights

This corrigendum addresses data overlap issues in Figures 4B and 6B of a previously published Oncology Reports article. Corrected figures are provided, and the overall conclusions remain unaffected by these data corrections.

Area of Science:

  • Biomedical Research
  • Oncology
  • Data Integrity

Background:

  • A previous study published in Oncology Reports (39: 1825-1834, 2018) contained data presentation errors.
  • Instances of data overlap were identified between panels in Figures 4B and 6B, suggesting data from the same source were presented as distinct experimental conditions.

Purpose of the Study:

  • To correct identified data overlap errors in Figures 4B and 6B.
  • To provide revised figures with accurate data panels for U87 and U251 cell lines.
  • To ensure the integrity of the published scientific record.

Main Methods:

  • Re-examination of original data files.
  • Identification of overlapping data panels in Figures 4B and 6B.
  • Retrieval and assembly of correct data panels.

Main Results:

  • Two pairs of overlapping data panels were found in Figure 4B (Mimics control and blank experiments for U87 and U251 cell lines).
  • One pair of overlapping data panels was identified in Figure 6B (miR‑375 mi + .pCDNA/RWDD3 and miR‑375 mi + .pCDNA experiments for U87 cell line).
  • Revised Figures 4 and 6 were generated with corrected data.

Conclusions:

  • The identified data errors were due to inadvertent incorrect assembly of figures.
  • The corrections do not alter the overall conclusions of the original study.
  • The authors apologize for any inconvenience caused to the readership.