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Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Influences of Different Operative Methods on the Recurrence Rate of Non-Muscle-Invasive Bladder Cancer.

Shoubin Li1, Yi Jia2, Chunhong Yu3

  • 1Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. lishoubin@163.com.

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|October 1, 2020
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Transurethral en bloc resection by pin-electrode (pin-ERBT) significantly reduces non-muscle-invasive bladder cancer recurrence compared to traditional TURBT and holmium laser methods. This finding offers a more effective treatment option for small bladder tumors.

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Area of Science:

  • Urology
  • Oncology
  • Surgical Innovation

Background:

  • Non-muscle-invasive bladder cancer (NMIBC) is the most common form of bladder cancer.
  • Recurrence is a significant challenge in managing NMIBC, necessitating effective surgical techniques.
  • Tumor size and operative approach influence recurrence rates.

Purpose of the Study:

  • To compare the efficacy of three surgical techniques in preventing recurrence of small NMIBC (<3 cm).
  • The techniques compared are transurethral en bloc resection by pin-electrode (pin-ERBT), transurethral resection of bladder tumor (TURBT), and transurethral holmium laser resection of bladder tumor (HoLRBT).

Main Methods:

  • A retrospective analysis of 115 patients with solitary NMIBC (diameter <3 cm) treated between March 2013 and May 2017.
  • Patients were categorized into pin-ERBT, TURBT, and HoLRBT groups.
  • Two-year recurrence rates were compared, and Cox hazard model analysis identified risk factors for recurrence.

Main Results:

  • The 2-year recurrence rates were 10.0% for pin-ERBT, 38.5% for TURBT, and 40.0% for HoLRBT (P=0.014).
  • Multivariate analysis identified age, operative method, smoking, and pathological grade as significant risk factors for recurrence.
  • Pin-ERBT demonstrated a significantly lower recurrence rate.

Conclusions:

  • Transurethral en bloc resection by pin-electrode (pin-ERBT) is superior in reducing postoperative recurrence for solitary NMIBC (<3 cm).
  • This technique offers a promising alternative for managing small NMIBC, potentially improving patient outcomes and reducing the need for repeat procedures.