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Preoperative localisation techniques in breast conservative surgery: A systematic review and meta-analysis
Inês C Moreira1, Sandra Rua Ventura2, Isabel Ramos3
1Faculty of Medicine of the University of Porto Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal; CINTESIS R. Dr. Plácido da Costa, 4200-450 Porto, Portugal; S. João Hospital Center, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal; Porto Health School Rua Dr. António Bernardino de Almeida 400, 4200 - 072, Porto, Portugal.
Radioactive Seed Localisation (RSL) and Radioactive Occult Lesion Localisation (ROLL) are superior to wire for non-palpable breast lesion excision, reducing reoperations. RSL may be preferred over ROLL, but further research is needed for newer techniques.
Area of Science:
- Breast Surgery
- Surgical Oncology
- Radiology
Background:
- Preoperative localization of non-palpable breast lesions is crucial for breast-conserving surgery.
- Various imaging-guided techniques exist for lesion localization.
Purpose of the Study:
- To systematically review and compare the clinical outcomes, patient-reported outcomes, and costs of different image-guided localization techniques for non-palpable breast lesions.
Main Methods:
- Systematic literature review and meta-analysis.
- Searched PubMed, ISI, SCOPUS, and Cochrane databases.
- Included 49 studies after screening 5720 articles.
Main Results:
- Radioactive Seed Localisation (RSL) and Radioactive Occult Lesion Localisation (ROLL) showed better outcomes regarding involved margins and reoperations compared to wire localization.
- A trend favored RSL over ROLL.
- Clip-guided localization may be preferable to ROLL, requiring further investigation.
Conclusions:
- RSL and ROLL are effective alternatives to wire localization for non-palpable breast lesions, offering easier implementation.
- Further research is necessary to establish robust evidence for newer localization techniques.
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