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Examining the Potential Relationship Between Multidisciplinary Team Meetings and Patient Survival in Pediatric
Suzan Dijkstra1, Kathelijne C J M Kraal, Veerle J Ruijters
1Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Insights
Multidisciplinary team meetings (MTMs) in pediatric oncology may improve survival, but evidence is limited. Further research is needed to confirm the survival benefits of MTMs for childhood cancer patients.
Area of Science:
- Pediatric Oncology
- Clinical Research Methodology
- Health Services Research
Background:
- Multidisciplinary team meetings (MTMs) are standard in pediatric oncology, believed to enhance communication and patient care.
- While MTMs' survival impact is studied in adults, its effect on pediatric cancer patients remains unclear.
Purpose of the Study:
- To systematically review the impact of MTMs on survival outcomes in pediatric oncology.
Main Methods:
- Searched MEDLINE/PubMed, EMBASE, and Cochrane Library databases up to January 2020.
- Included 5 studies (1 prospective, 4 retrospective cohort) after screening 325 records.
- Analyzed studies comparing survival in MTM-discussed versus non-MTM patients.
Main Results:
- Three of the 5 included studies found a statistically significant association between MTMs and improved overall or event-free survival.
- Study quality was limited by design, and significant clinical and methodological heterogeneity was noted.
Conclusions:
- A definitive causal link between MTMs and improved survival in pediatric cancer cannot be established due to limited, heterogeneous studies.
- Further high-quality research is essential to validate MTMs' survival benefits and guide resource allocation for optimal childhood cancer care.
Abstract:
The organization of multidisciplinary team meetings (MTMs) has become standard practice in pediatric oncology and is widely felt to improve communication, knowledge, and patient care. Although the impact of MTMs on survival in adult oncology has been extensively researched, the potential benefits of survival for pediatric cancer patients are still unclear. This systematic review aimed to examine the impact of MTMs on survival in pediatric oncology settings. Relevant studies were identified by searching MEDLINE/PubMed, EMBASE, and the Cochrane Library databases up to January 2020, resulting in 325 unique records. After the title/abstract and full-text screening, 5 studies were included. All of the included studies (one prospective and 4 retrospective cohort studies) described a difference in overall or event-free survival when comparing patients who were discussed in MTMs with non-MTM patients. This association was statistically significant in 3 studies. The quality of the studies was strongly affected by their design. Because of the small number of studies in combination with high clinical and methodological heterogeneity, this review was unable to definitively assert a causal relationship between MTMs and survival in pediatric cancer patients. Further research is needed to explore this relationship and allow cost-benefit analyses, so that time and resources are optimally spent to deliver the best possible care to childhood cancer patients.
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