Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

31.3K
Overview
31.3K
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

507
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
507
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.2K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.2K
Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

622
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
622
Chronic Pharyngitis01:23

Chronic Pharyngitis

8.9K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
8.9K
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

880
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
880

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.

Journal of clinical medicine·2026
Same author

IgE-mediated cocoa allergy: a pediatric case report and review of the literature.

Frontiers in pediatrics·2026
Same author

Macrolide-induced hypersensitivity reactions in the pediatric population.

Italian journal of pediatrics·2026
Same author

<i>PHOX2B</i> Tyr14Ter Mutation Might Be Associated with Sustained Diurnal Hypertension: Case Report and Review of the Literature.

Children (Basel, Switzerland)·2026
Same author

Multidisciplinary Delphi Consensus on management of children with moderate-severe atopic dermatitis.

Italian journal of pediatrics·2026
Same author

IgE to cyclophilin Bet v 7 triggers mast cell activation and mediates cross-reactivity with Ara h 18 in children with seasonal allergic rhinitis.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2026
Same journal

An unusual cause of obstructing laryngeal edema: Forestier's disease. <b>Case report and literature review</b>.

Acta bio-medica : Atenei Parmensis·2026
Same journal

IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report.

Acta bio-medica : Atenei Parmensis·2023
Same journal

Acute paraplegia in a patient with eosinophilic granulomatosis and polyangiitis with 20 years of evolution: case report.

Acta bio-medica : Atenei Parmensis·2023
Same journal

SARS-CoV-2 infection in meat and poultry workers after the "first wave" (Summer 2020): a cross-sectional study on knowledge, attitudes, practices (KAP) of Italian occupational physicians.

Acta bio-medica : Atenei Parmensis·2023
Same journal

The impact of pediatric congenital heart disease on primary teeth structure: a histological study.

Acta bio-medica : Atenei Parmensis·2023
Same journal

Predictors of neuropathic dysesthetic pain occurrence and chronification in multiple sclerosis (2-year prospective study).

Acta bio-medica : Atenei Parmensis·2023
See all related articles

Related Experiment Video

Updated: Dec 7, 2025

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.3K

Allergic rhinoconjunctivitis.

Michele Miraglia Del Giudice1, Annalisa Allegorico2, Gian Luigi Marseglia3

  • 1Department of Woman, Child and of General and Specialized Surgery. University of Campania "Luigi Vanvitelli" Naples, Italy. michele.miraglia@unicampania.it.

Acta Bio-Medica : Atenei Parmensis
|October 2, 2020
PubMed
Summary
This summary is machine-generated.

Allergic rhinitis (AR) involves IgE-mediated reactions causing nasal symptoms. Diagnosis requires matching symptoms with tests like the skin prick test (SPT), with treatments including antihistamines and intranasal steroids.

More Related Videos

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.0K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

2.8K

Related Experiment Videos

Last Updated: Dec 7, 2025

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.3K
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.0K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

2.8K

Area of Science:

  • Immunology
  • Allergology
  • Otolaryngology

Background:

  • Allergic rhinitis (AR) is an IgE-mediated immune response to allergens.
  • Common symptoms include itching, rhinorrhea, sneezing, and nasal congestion.
  • AR frequently co-occurs with other atopic conditions.

Purpose of the Study:

  • To summarize the understanding of allergic rhinitis.
  • To outline diagnostic approaches and treatment options.
  • To highlight the systemic nature of allergic rhinitis.

Main Methods:

  • Literature review of allergic rhinitis pathogenesis, diagnosis, and treatment.
  • Emphasis on IgE-mediated mechanisms and allergen exposure.
  • Discussion of diagnostic concordance between symptoms and tests.

Main Results:

  • Skin prick test (SPT) is the gold standard for diagnosis.
  • First-generation H1-antihistamines are common treatments.
  • Intranasal glucocorticosteroids are effective and suitable for pediatric use.

Conclusions:

  • Allergic rhinitis requires accurate diagnosis correlating symptoms with testing.
  • Pharmacological treatments like antihistamines and intranasal steroids are effective.
  • AR is often part of a broader atopic profile, necessitating a holistic approach.