Related Experiment Video
Updated: Dec 7, 2025

05:41
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
928
Thyroid Disease Spectrum in the Emergency Department
Mariana Formigo1, Gonçalo Castelo Branco1, Magda Fernandes1
1Internal Medicine, Hospital Senhora da Oliveira Guimarães, Guimarães, PRT.
Cureus
|October 2, 2020
Summary
Thyroid hormone imbalances can manifest as medical emergencies. Early diagnosis and treatment of severe hyperthyroidism and hypothyroidism are crucial for patient recovery and preventing severe symptoms.
Area of Science:
- Endocrinology
- Internal Medicine
- Neurology
Background:
- Thyroid hormone disorders, including hyperthyroidism and hypothyroidism, can present with diverse and severe clinical manifestations.
- Prompt recognition and management are essential to prevent potentially life-threatening complications.
Observation:
- A 56-year-old woman presented with acute psychomotor agitation and disorientation, diagnosed as severe hyperthyroidism.
- A 54-year-old woman exhibited significant memory and behavioral changes, later diagnosed as severe hypothyroidism.
Findings:
- The first patient's hyperthyroidism resolved with propylthiouracil treatment.
- The second patient's hypothyroidism improved with levothyroxine, with normalized thyroid function and ultrasound, and elevated antithyroperoxidase antibodies.
Implications:
- These cases highlight the critical need for early diagnosis of thyroid emergencies.
- Timely intervention with appropriate medication is vital for successful patient outcomes in thyroid dysfunction.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
6.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
6.7K
The Thyroid Gland
6.2K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.2K
Introduction Cardiac Emergencies
226
Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
226
Functions of Thyroid Hormones
4.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.6K
Adrenal Gland Disorders
2.7K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
2.7K
Acute Coronary Syndrome III: Diagnostic Studies
118
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
118

