Related Experiment Video
Updated: Dec 7, 2025

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest
Published on: August 6, 2015
Death due to Cardiac Arrest in a Young Female With Highly Suspected COVID-19: A Case Report
Sherif Mohamed1, Osama Abo El-Hassan2, Magda Rizk3
1Chest Diseases and Tuberculosis, Faculty of Medicine, Assiut University, Assiut, EGY.
Insights
A young, seemingly healthy patient experienced cardiac arrest and died from COVID-19, despite initial negative tests. This case highlights rare severe COVID-19 presentations and the risk of pulmonary thromboembolism in younger individuals.
Area of Science:
- Medicine
- Infectious Diseases
- Cardiology
Background:
- Common COVID-19 presentations and risk factors are known, but rare and atypical cases, including in younger individuals, persist.
- Younger patients without typical risk factors can still experience severe outcomes from COVID-19.
Abstract:
Despite the common clinical presentations of the pandemic coronavirus disease of 2019 (COVID-19) being well-known, there remain issues on its atypical or rare presentations. Moreover, despite the known risk factors for severe COVID-19 are cardiovascular disease, diabetes mellitus, hypertension, chronic lung disease, and advanced age, still younger patients suffer from this disease. Herein, we present a case report of a 28-year-old female patient who was presented to the ED with cardiac arrest, then died within 12 hours. First swab testing by reverse transcription-polymerase chain reaction (RT-PCR) came negative. However, she has typical CT features of COVID-19 pneumonia, along with an echocardiographic picture of acute cor pulmonale. Though it is rare, cardiac arrest can happen in young apparently healthy patients with COVID-19. As COVID-19 patients are commonly having clotting disorders, endothelial and organ dysfunction, coagulopathy, and liable for pulmonary thromboembolism (PTE), it is important to select those COVID-19 patients who are at higher risk of PTE, and practice CT pulmonary angiography (CTPA) for the diagnosis of PTE, especially in case of significant increase of D-dimer values.
Related Concept Videos
Coronary Artery Disease III: Clinical Manifestations
Introduction Cardiac Emergencies
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation III: AED Use
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy

