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Updated: Aug 12, 2026

Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
Lymphocyte populations in peripheral blood during normal human pregnancy
The effects of normal pregnancy on peripheral blood lymphocytes were investigated. The frequencies of thymus-derived and bone-marrow-derived lymphocytes in maternal peripheral blood does not vary significantly throughout pregnancy. This observation implies qualitative rather than quantitative alterations in lymphocyte functions to explain the reduced cell-mediated immune responses seen during pregnancy.
The effects of normal pregnancy on peripheral blood lymphocytes were investigated. The frequencies of thymus-derived and bone-marrow-derived lymphocytes in maternal peripheral blood does not vary significantly throughout pregnancy. This observation implies qualitative rather than quantitative alterations in lymphocyte functions to explain the reduced cell-mediated immune responses seen during pregnancy.
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