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Updated: Dec 7, 2025

The Influence of Liver Resection on Intrahepatic Tumor Growth
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Benign Liver Tumors.

Karl J Oldhafer1,2, Victoria Habbel1,2, Katja Horling3

  • 1Department für Chirurgie, Klinik für Leber-, Gallenwegs- und Pankreaschirurgie, Asklepios Klinik Barmbek, Hamburg, Germany.

Visceral Medicine
|October 2, 2020
PubMed
Summary

Benign liver tumors like hemangiomas, FNH, and HCA are common and often asymptomatic. Advanced imaging allows accurate diagnosis, minimizing the need for biopsies and treatment in most cases.

Keywords:
Benign liver tumorsFocal nodular hyperplasiaHemangiomaHepatocellular adenoma

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Area of Science:

  • Hepatology
  • Diagnostic Imaging
  • Gastroenterology

Background:

  • Increasing incidence of benign liver tumors due to widespread medical imaging.
  • Common types include hepatic hemangioma (HH), focal nodular hyperplasia (FNH), and hepatocellular adenoma (HCA).
  • Most benign liver tumors are asymptomatic and require no treatment; complications include bleeding and malignant transformation.

Purpose of the Study:

  • To review clinical presentations, treatment options, and management strategies for HH, FNH, and HCA.
  • To highlight the diagnostic capabilities of advanced imaging techniques.
  • To differentiate the risks and management of various benign liver tumor types.

Main Methods:

  • Review of clinical literature on hepatic hemangioma, FNH, and HCA.
  • Analysis of diagnostic imaging modalities for benign liver tumors.
  • Evaluation of treatment strategies including surgical, interventional, and conservative management.

Main Results:

  • Accurate diagnosis is achievable with modern imaging, reducing the need for biopsies.
  • Hepatic hemangiomas may require liver resection, ablation, or embolization.
  • FNH rarely transforms malignantly and requires treatment only if symptomatic.
  • Hepatocellular adenoma carries a risk of malignant transformation and has diverse subtypes with varying risks.

Conclusions:

  • The majority of benign liver tumors are asymptomatic and do not necessitate intervention.
  • Advanced imaging techniques are crucial for accurate diagnosis, often obviating the need for biopsies.
  • Management strategies vary significantly among HH, FNH, and HCA, with HCA posing unique risks.