Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

9.5K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
9.5K
Bone Cells and Tissue01:30

Bone Cells and Tissue

7.5K
Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
7.5K
Compact Bone01:27

Compact Bone

15.4K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
15.4K
Bone Markings01:26

Bone Markings

7.6K
Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
7.6K
Bone Structure01:55

Bone Structure

51.0K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
51.0K
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

7.5K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
7.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ploidy shapes gemcitabine response through altered potency and delayed cell death.

bioRxiv : the preprint server for biology·2026
Same author

Support for Older People With Vision Impairment: A Rapid Realist Review.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same author

Current Advances and Controversies in Spine Imaging.

Seminars in musculoskeletal radiology·2026
Same author

Role of chest imaging in GCTB staging and surveillance.

Clinical imaging·2026
Same author

Pitfalls in Imaging of Spinal Infection.

Seminars in musculoskeletal radiology·2026
Same author

Impact of surgical timing on wound complications following ankle fracture fixation: A 22-year retrospective cohort study.

Journal of clinical orthopaedics and trauma·2026

Related Experiment Video

Updated: Dec 7, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
04:25

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

10.8K

Intraosseous lipomas originating from simple bone cysts.

Bernhard J Tins1, Yaron J Berkowitz2, Praveen Konala3

  • 1Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Oswestry, Shropshire, SY10 7AQ, UK. btins@nhs.net.

Skeletal Radiology
|October 2, 2020
PubMed
Summary
This summary is machine-generated.

Simple bone cysts (SBCs) can heal by developing into fatty lesions that resemble intraosseous lipomas. This study provides evidence that some intraosseous lipomas may actually be healed SBCs.

Keywords:
Intraosseous lipomaPrecursor lesionProgressionSimple bone cystTransformation

More Related Videos

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
08:52

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Published on: June 13, 2018

9.1K
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

236

Related Experiment Videos

Last Updated: Dec 7, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
04:25

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

10.8K
Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
08:52

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells

Published on: June 13, 2018

9.1K
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

236

Area of Science:

  • Orthopedic imaging
  • Skeletal radiology
  • Bone pathology

Background:

  • Intraosseous lesions, including fatty or part-fatty types, are frequently observed in skeletal imaging.
  • Previous case reports suggest calcaneal bone cysts may involute into intraosseous lipomas, but this remains unproven.

Purpose of the Study:

  • To investigate and demonstrate that simple bone cysts (SBCs) can involute into fatty lesions.
  • To determine if these fatty lesions are indistinguishable from intraosseous lipomas.

Main Methods:

  • Retrospective analysis of pathology and PACS databases from two orthopedic hospitals (August 2007–December 2016).
  • Inclusion criteria: intraosseous lipomas with observed imaging changes, or SBCs with cross-sectional imaging follow-up.

Main Results:

  • No intraosseous lipoma cases showed changes in imaging appearance.
  • Six cases of SBC with follow-up imaging were identified, all demonstrating peripheral fatty infiltration.
  • Two SBCs showed complete fatty conversion, while four showed partial fatty conversion.

Conclusions:

  • Simple bone cysts (SBCs) have the capacity to heal through fatty conversion of the cystic cavity.
  • Partially or completely healed SBCs can present imaging characteristics similar to intraosseous lipomas.
  • It is proposed that a subset of lesions currently diagnosed as intraosseous lipomas are, in fact, healed SBCs.