[Thrombocytopenia and thromboses in a young woman]

This article reports the case of a 34-year-old female patient with multiple thrombotic events (cerebral venous sinus thrombosis, ischemic duodenitis) with simultaneous thrombocytopenia (ca. 70/nl). A paroxysmal nocturnal hemoglobinuria without detectable hemolysis and with simultaneous myelodysplastic syndrome was causative for these symptoms. This rare disease is important to consider in the differential diagnosis of chronic inflammatory rheumatic diseases, such as systemic lupus erythematosus, antiphospholipid antibody syndrome and vasculitis.