Related Experiment Video
Updated: Dec 7, 2025

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
Published on: October 4, 2024
Normal ranges of renal function parameters for 99mTc-EC renal scintigraphy
Agata Danilczuk1, Anna Nocun2, Beata Chrapko2
1Medical Univercity of Lublin, Poland. agata@swietlicki.net.
Background:
Dynamic renal scintigraphy remains the recognized method for evaluation of kidney function and perfusion. Although there is an extensive body of knowledge about the use of technetium-99m-mercaptoacetyltriglycine (99mTc-MAG3), much less has been written about renal technetium-99m-ethylenedicysteine (99mTc-EC) scintigraphy. The aim of this study was to determine the normal value of renal function parameters in 99mTc-EC dynamic renal scintigraphy: Tmax and T1/2. The effects of age, left or right side in the retroperitoneal space, and sex on those parameters were examined.
Material And Methods:
The research was conducted on 123 patients (F/M: 70/53; aged 2-71; averaging 14.8 years of age) with at least one normal kidney. A total of 194 healthy kidneys were examined, including pediatric kidneys.
Results:
According to this study, the normal value of Tmax is 2.85 min (± 1.16) and T1/2 is 8.7 min (± 3.61). Values calculated for pediatric studies are Tmax is 2.81 (± 1.16) and T1/2 is 8.63 (± 3.71).
Conclusions:
The normal value of secretory and excretory renal function parameters was calculated. Although the value is slightly lower for children, this is not statistically significant, as globally there are no differences between the kidney-location sides and sexes for any parameter.
More Related Videos
09:49A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
06:54MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
Related Concept Videos
Serum Studies: Renal Function Tests
Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies III: Computed Tomography
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Imaging Studies IV: Magnetic Resonance Imaging