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Normal ranges of renal function parameters for 99mTc-EC renal scintigraphy
Agata Danilczuk1, Anna Nocun2, Beata Chrapko2
1Medical Univercity of Lublin, Poland. agata@swietlicki.net.
This study establishes normal values for renal function parameters using technetium-99m-ethylenedicysteine (99mTc-EC) dynamic renal scintigraphy. No significant differences were found based on age, sex, or kidney location.
Area of Science:
- Nuclear Medicine
- Renal Physiology
- Diagnostic Imaging
Background:
- Dynamic renal scintigraphy is crucial for assessing kidney function and perfusion.
- Technetium-99m-mercaptoacetyltriglycine (99mTc-MAG3) is widely used, but less is known about technetium-99m-ethylenedicysteine (99mTc-EC).
Purpose of the Study:
- To determine normal values for Tmax and T1/2 in 99mTc-EC dynamic renal scintigraphy.
- To investigate the influence of age, sex, and kidney laterality on these parameters.
Main Methods:
- Analysis of 194 healthy kidneys from 123 patients (aged 2-71 years).
- Inclusion of both adult and pediatric kidneys in the study cohort.
Main Results:
- Normal Tmax value established at 2.85 min (± 1.16) and T1/2 at 8.7 min (± 3.61).
- Pediatric values (Tmax: 2.81 ± 1.16 min, T1/2: 8.63 ± 3.71 min) showed no statistical significance compared to adults.
Conclusions:
- Established normal secretory and excretory renal function parameters for 99mTc-EC scintigraphy.
- No statistically significant differences observed across age groups, sexes, or kidney locations.
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