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Assessment of Midline Lingual Point-Pressure Somatosensation Using Von Frey Hair Monofilaments
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SnapShot: Orofacial Sensation.

Patrick Delmas1, Bertrand Coste1

  • 1Laboratoire de Neurosciences Cognitives, Aix-Marseille-Université, CNRS, UMR 7291, Marseille, France.

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|October 2, 2020
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Summary
This summary is machine-generated.

The trigeminal nerve

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Area of Science:

  • Neuroscience
  • Sensory Biology
  • Molecular Biology

Background:

  • The trigeminal nerve's ophthalmic, maxillary, and mandibular branches innervate orofacial tissues.
  • Trigeminal sensory neurons process diverse stimuli like temperature, touch, itch, and pain.
  • These neurons are also involved in detecting the pungency of food and beverages.

Purpose of the Study:

  • To highlight the critical transduction ion channels involved in orofacial sensation.
  • To provide an overview of the molecular mechanisms underlying trigeminal sensory perception.

Main Methods:

  • This review focuses on ion channels crucial for sensory transduction in trigeminal neurons.
  • It synthesizes current knowledge on molecular players in orofacial sensation.

Main Results:

  • Specific ion channels mediate distinct orofacial sensations, including thermosensation and mechanosensation.
  • These channels are essential for detecting various stimuli, from physical touch to chemical irritants in food.
  • Dysregulation of these channels can lead to orofacial pain and altered sensory perception.

Conclusions:

  • Transduction ion channels are fundamental to the function of trigeminal sensory neurons.
  • Understanding these channels is key to addressing orofacial sensory disorders and pain.
  • This knowledge advances our comprehension of sensory processing in the head and face.