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Epidemiology of Pediatric Hypertrophic Cardiomyopathy in a 10-Year Medicaid Cohort

Deipanjan Nandi1, Emily A Hayes1, Yinding Wang2

  • 1The Heart Center, Nationwide Children's Hospital, Columbus, OH, USA.

Pediatric Cardiology
|October 3, 2020
PubMed

Insights

Epidemiologic data for pediatric hypertrophic cardiomyopathy (HCM) were updated using a 10-year Medicaid database. Pediatric HCM prevalence was 1.2/1,000,000, with higher rates than previous estimates.

Area of Science:

  • Cardiology
  • Pediatrics
  • Epidemiology

Background:

  • Pediatric hypertrophic cardiomyopathy (HCM) data require updates due to evolving diagnostic and management techniques.
  • Understanding the epidemiology of pediatric HCM is crucial for public health initiatives and resource allocation.

Purpose of the Study:

  • To determine the incidence, prevalence, and mortality rates of pediatric hypertrophic cardiomyopathy (HCM) within a population-based treatment system.
  • To provide updated epidemiologic data for pediatric HCM in a Southeast US statewide service system.

Main Methods:

  • Analysis of a 10-year (2007-2016) Medicaid database for patients aged ≤17 years diagnosed with HCM.
  • Inclusion of 137 unique pediatric patients, examining demographic data, comorbidities, and mortality.
  • Calculation of 10-year prevalence and annual incidence rates for pediatric HCM.

Main Results:

  • The 10-year prevalence of pediatric HCM was 1.2 per 1,000,000; the 2010 annual incidence was 1.3 per 100,000.
  • Cardiac-related mortality was 2.9%, with 70% of deaths occurring in infants ≤13 months.
  • Common comorbidities included arrhythmia (30.7%), heart failure (12.4%), and malformation syndromes (13.1%); 75.9% were idiopathic HCM.

Conclusions:

  • The study provides updated epidemiologic data for pediatric HCM, with prevalence and incidence rates potentially higher than previously reported estimates.
  • Findings highlight the significant burden of pediatric HCM, particularly in infants, and the need for continued surveillance and research.
  • The data augment existing knowledge and are representative of a Southeast US statewide service system.

Keywords:
ArrhythmiaEpidemiologyHeart failurePediatric hypertrophic cardiomyopathy

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