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Updated: Dec 7, 2025

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Bioabsorbable interference screws can be used with less tunnel widening in anatomic rectangular tunnel anterior
Kousuke Shiwaku1, Tomoyuki Suzuki1, Takashi Matsumura1
1Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
Background:
The purpose of this study was to investigate postoperative tunnel widening after rectangular tunnel bone-patellar-tendon-bone graft anterior cruciate ligament reconstruction using newer-generation bioabsorbable interference screws.
Methods:
Forty-six patients who had undergone primary rectangular tunnel bone-patellar-tendon-bone graft anterior cruciate ligament reconstruction using MILAGRO bioabsorbable interference screws (DePuy Synthes, Warsaw, IN, USA) for femoral fixation and for whom computed tomography was performed at two weeks and one year postoperatively were included in this prospective study. To assess the tunnel widening, the cross-sectional area of the femoral tunnel aperture (compared between two weeks and one year postoperatively) was assessed using computed tomography. Cyst formation, postoperative screw breakage, screw migration, and graft migration were also evaluated using computed tomography one year postoperatively.
Results:
Mean tunnel widening was 1.9%, and the cross-sectional area of the femoral tunnel aperture was not significantly different between two weeks and one year postoperatively. Postoperative cyst formation, screw breakage, screw migration, and graft migration were not observed in any patient.
Conclusions:
After rectangular tunnel bone-patellar-tendon-bone graft anterior cruciate ligament reconstruction using bioabsorbable interference screws for femoral fixation, tunnel widening was not observed via computed tomography analysis at two weeks and one year postoperatively.
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