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The Impact of Cancer on Early Childhood Development: A Linked Data Study
Julia N Morris1, David Roder2, Deborah Turnbull3
1Behavioural Research and Evaluation Unit, Cancer Council South Australia.
Insights
Childhood cancer survivors showed increased developmental vulnerability in physical health. Remoteness appeared protective for developmental outcomes, highlighting the need for targeted support for these children.
Area of Science:
- Pediatric oncology
- Developmental psychology
- Public health
Background:
- Early childhood cancer significantly impacts a child's life.
- Understanding long-term developmental outcomes is crucial for survivors.
- Population-level data offers insights into cancer survivorship.
Purpose of the Study:
- To investigate the impact of early childhood cancer on developmental outcomes.
- To identify factors influencing developmental trajectories in childhood cancer survivors.
- To assess the utility of administrative data for cancer outcome research.
Main Methods:
- Retrospective linkage of South Australian Cancer Registry data with Australian Early Development Census (AEDC) data.
- Inclusion of children diagnosed with malignant neoplasms before age 9.
- Matched survivor-to-control design using five controls per survivor from the AEDC.
Main Results:
- Childhood cancer survivors exhibited greater developmental vulnerability in physical health and wellbeing compared to controls.
- No significant differences were found in social, emotional, language, cognitive, communication, or general knowledge domains.
- Living in rural or remote areas was a protective factor for developmental outcomes, particularly physical health and wellbeing.
Conclusions:
- Children diagnosed with early cancer may need targeted support for physical health and wellbeing.
- Geographic variations in developmental outcomes, especially the protective effect of remoteness, warrant further investigation.
- Administrative whole-population data is a feasible resource for studying cancer outcomes.
Objective:
This study used retrospective linked population data to investigate the impact of early childhood cancer on developmental outcomes.
Methods:
Children aged <9 years with a recorded malignant neoplasm were identified in the South Australian Cancer Registry. They were then linked to developmental data recorded in the Australian Early Development Census (AEDC) for the 2009, 2012, and 2015 data collection periods; and assigned five matched controls from the same AEDC year.
Results:
Between 2000 and 2015, 43 children had a malignant cancer diagnosis and also participated in the AEDC. Compared to controls, childhood cancer survivors exhibited greater developmental vulnerability in their physical health and wellbeing. Between survivors and controls, no significant developmental differences were observed in social, emotional, language and cognitive, and communication and general knowledge domains. Rural or remote location had a significant positive effect on developmental outcomes for childhood cancer survivors relative to controls, suggesting this was a protective factor in terms of physical health and wellbeing, social competence, communication, and general knowledge. Among all children, socioeconomic advantage was linked to better developmental outcomes on all domains except physical health and wellbeing.
Conclusion:
Following an early cancer diagnosis, children may require targeted care to support their physical health and wellbeing. Geographic variation in developmental outcomes indicates remoteness was a protective factor and requires further investigation. This study highlights the feasibility of using administrative whole-population data to investigate cancer outcomes.
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