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COVID-19 and the Heart

Chaitanya Rojulpote1,2, Karthik Gonuguntla3, Shivaraj Patil3

  • 1University of Pennsylvania, Departments of Medicine and Radiology, Philadelphia, United States.

Colombia Medica (Cali, Colombia)
|October 5, 2020
PubMed

Insights

The COVID-19 pandemic poses a double threat to individuals with existing cardiovascular disease. This review explores how SARS-CoV-2 impacts the heart and potential treatment effects.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, presents a significant global health challenge.
  • Cardiovascular diseases (CVD) were already a major global health burden before the pandemic.
  • Individuals with cardio-metabolic disorders face increased mortality risk from COVID-19.

Purpose of the Study:

  • To discuss the cardiovascular effects of COVID-19.
  • To explore the potential mechanisms underlying these effects.
  • To consider the cardiovascular implications of COVID-19 treatments.

Main Methods:

  • Literature review and synthesis of existing data.
  • Analysis of early reports and prior viral epidemic studies.
  • Discussion of direct and indirect pathophysiological pathways.

Main Results:

  • COVID-19 can potentially trigger acute coronary syndromes, arrhythmias, and heart failure.
  • Mechanisms include direct viral effects and indirect inflammatory responses.
  • Emerging evidence suggests significant cardiovascular morbidity and mortality in COVID-19 patients with pre-existing conditions.

Conclusions:

  • COVID-19 exacerbates the burden of cardiovascular disease.
  • Understanding the cardiovascular impact of SARS-CoV-2 is crucial for patient management.
  • Further research is needed to elucidate mechanisms and guide therapeutic strategies for cardiovascular complications.

Keywords:
COVID-19SARS-CoV-2acute coronary syndromesarrhythmiascardio-metabolic disorderscardiovascular diseaseheart failure

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