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What are the principles that govern life?

Jaime Gómez-Márquez1

  • 1Department of Biochemistry and Molecular Biology, Faculty of Biology - CIBUS, University of Santiago de Compostela, Galicia, Spain.

Communicative & Integrative Biology
|October 5, 2020
PubMed
Summary

Life requires new biological principles beyond physics and chemistry. This study proposes seven "commandments of life" to explain biological phenomena from an evolutionary viewpoint.

Keywords:
Life rulescooperativityentropy and lifeevolutionreformulated central dogmavital determinism

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Area of Science:

  • Theoretical Biology
  • Evolutionary Biology
  • Biophysics

Background:

  • Universal laws of physics and chemistry govern living matter.
  • These laws alone are insufficient to explain the unique characteristics of life.
  • A theoretical framework for understanding life necessitates intrinsic biological principles.

Purpose of the Study:

  • To propose a set of principles for a theoretical framework of life.
  • To explain the vital phenomenon from an evolutionary perspective.
  • To introduce the 'seven commandments of life'.

Main Methods:

  • Conceptual framework development.
  • Identification of core biological principles.
  • Metaphorical representation of life as an evolutionary race.

Main Results:

  • Proposal of the seven commandments of life: Vital Order, Principle of Inexorability, reformulated Central Dogma, Tyranny of Time, Evolutionary Imperative, Conservative Rule, and Cooperating Thrust.
  • These principles offer a new perspective on understanding life's characteristics.
  • The commandments provide rules for the evolutionary process.

Conclusions:

  • The seven commandments of life offer a foundational set of principles for a theoretical biology.
  • Understanding life requires principles intrinsic to biology, viewed through an evolutionary lens.
  • Life's complexity can be better explained by these proposed biological rules.