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Updated: Dec 6, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Treatment of Metabolic Syndrome in Children
Veronica Maria Tagi1, Sona Samvelyan1, Francesco Chiarelli2
1Department of Paediatrics, University of Chieti, Chieti, Italy.
Abstract:
Although metabolic syndrome (MetS) in children and adolescents is a frequently discussed topic in the literature, uniform guidelines on its definition and treatment are still lacking. Insulin resistance, central obesity, dyslipidaemia, and hypertension are commonly considered the main components of MetS. The first recommended approach to all these pathological conditions in children and adolescents is lifestyle intervention (diet and physical exercise); however, in some selected cases, a pharmacological or surgical treatment might prove useful for the prevention of metabolic and cardiovascular complications. The aim of this review is to present the more recent evidence about the treatment of the major components of MetS in children and adolescents, focussing on the current recommendations concerning lifestyle changes, available drugs, and bariatric surgery.
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