Open-source 128-channel bioamplifier module for ambulatory monitoring of gastrointestinal electrical activity

We present an open-source, low-cost, portable, 128-channel bioamplifier module designed specifically for ambulatory, long-term (≥24 hr) monitoring of gastrointestinal (GI) electrical activity. The electronics hardware integrates stateof-the-art, commercial-off-the-shelf components on a custom PCB. Features include on-board data logging, wireless data streaming, subject motion monitoring, and stable operation up to the maximum 2 kHz/channel sampling rate tested. The new device operates for ≈ 30 hr continuously powered by a single 3.7 V, 2500 mAh LiPo battery. The 3D-printed ABS mechanical enclosure is robust and small (13.1 × 8.8 × 2.5 cm), so that the device can be carried in a standard Holter monitor pouch. Results from initial 128-channel, high spatial resolution body surface colon mapping experiments demonstrate the utility of this new device for GI applications. The new bioamplifier module could also be used for multichannel recording experiments in a variety of biomedical domains to study electrical activity patterns of the neuromuscular system (EMG), uterus (EHG), heart (ECG), and brain (EEG).