Regulation of glucose transport in Aspergillus nidulans

Pyruvate and acetate inhibited the uptake of glucose by Aspergillus nidulans; although there were significant variations in glucose uptake rate, the intracellular concentration of acetate was almost identical in biotin-supplemented, normal and deficient cells. The in vitro activity of glucose-binding protein was not affected by biotin, avidin, acetate or acetyl-CoA.