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Diffuse primary extra-gastrointestinal stromal tumor of the peritoneum: A rare case report
Liang-Ji Lu1, Xiao-Pei Xu1, Fei Dong1
1Department of Radiology, the Second Affiliated Hospital, Zhejiang University School of Medicine.
Rationale:
Gastrointestinal stromal tumors that present outside the gastrointestinal tract are known for extra-gastrointestinal stromal tumors (EGISTs) and they share the same morphological and immunohistochemical characteristics with gastrointestinal stromal tumors. Here we report a rare case of diffuse primary EGIST arising at peritoneum.
Patient Concerns:
A 57-year-old male presented to the hospital with abdominal pain and right lower abdominal tenderness.
Diagnosis:
The core needle puncture biopsy showed epithelial-like cells and the nuclei were ovoid and focally elongated. Immunohistochemical examination was consistent with a primary EGIST of the peritoneum.
Interventions:
The patient was treated with Imatinib mesylate.
Outcomes:
Five months later, there is no complication resulting from treatment. The follow-up abdominal contrast-enhanced CT showed the lesion was significantly decreased in size, and was evaluated as partial response. The patient continued the treatment with Imatinib as prescribed by the oncologist.
Lessons:
EGISTs are rare and should be considered in the differential diagnosis of the peritoneal tumors and immunohistochemistry helps to confirm the diagnosis. Further study with longer follow-up is desired to characterize these uncommon tumors.
