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Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library
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Dissecting the Interaction of FGF8 with Receptor FGFRL1

Lei Zhuang1, Monique Vogel1, Peter M Villiger2

  • 1Department for BioMedical Research, University of Bern, 3008 Bern, Switzerland.

Biomolecules
|October 6, 2020
PubMed
Summary

Fibroblast growth factor receptor-like 1 (FGFRL1) is crucial for kidney development, interacting with FGF8 to form nephrons. The Ig2 domain of FGFRL1 is key for this high-affinity binding during kidney formation.

Keywords:
FGF8FGFRL1fibroblast growth factor (FGF)fibroblast growth factor receptor (FGFR)kidney developmentmesenchymal-to-epithelial transition (MET)

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