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The Human Respiratory System and its Microbiome at a Glimpse
Luigi Santacroce1,2, Ioannis Alexandros Charitos3, Andrea Ballini4,5
1Ionian Department, Microbiology and Virology Laboratory, University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.
Biology
|October 6, 2020
Summary
The respiratory microbiome
Area of Science:
- Microbiology
- Immunology
- Human Physiology
Background:
- The COVID-19 pandemic highlighted the need to understand the respiratory microbiome's role in health and disease.
- The respiratory tract harbors a complex microbial community influencing host immunity and pathogen interactions.
Purpose of the Study:
- To review the physiological functions of the respiratory microbiome.
- To examine the respiratory microbiome's composition, evolution, and stability.
- To explore the interplay between the respiratory and intestinal microbiomes.
Main Methods:
- Literature review of existing studies on the respiratory microbiome.
- Analysis of factors influencing respiratory microbiota composition (age, diet).
- Examination of the microbiome's functional roles and interactions.
Main Results:
- The respiratory microbiome's composition varies with age and external factors.
- Commensal, symbiotic, and pathogenic microbes play crucial roles.
- The respiratory microbiome is increasingly linked to the intestinal microbiome and overall health.
Conclusions:
- Maintaining the respiratory micro-ecosystem is vital for human health.
- Understanding the respiratory microbiome aids in managing respiratory diseases.
- Further research into the respiratory microbiome's functions and interactions is warranted.
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